Advanced Biomaterials and Tissue Engineering
| Keywords |
| Classification |
Keyword |
| OFICIAL |
Science and Technology of Materials |
Instance: 2023/2024 - 1S 
Cycles of Study/Courses
| Acronym |
No. of Students |
Study Plan |
Curricular Years |
Credits UCN |
Credits ECTS |
Contact hours |
Total Time |
| M.EMAT |
9 |
Syllabus |
2 |
- |
6 |
39 |
162 |
Teaching Staff - Responsibilities
Teaching language
Portuguese and english
Objectives
This subject aims at providing the students the required preparation so as to acquire the advanced know-how in Biomaterials in terms of structures, surfaces and their properties, in particular in their specific relationship with the biologic environment where they are expected to reside and perform their functions. Therefore within this subject students shall aim at becoming capable to develop and characterize in the many different situations the biomaterials, when integrating specific medical devices. They shall also gain capability of establishing critical analyses and capacity to solve problems both technical and scientific, and to look in a critic and selective way to the scientific information available at the state of the art level in a specific theme and also the capability to carry out RD& D involving Biomaterials.
Learning outcomes and competences
Based on the students that shall be involved in this subject, that may derive from very different and heterogeneous backgrounds, the first part of this subject shall allow them to rise to a common ground of knowledge allowing them to follow and have participation adjusted to the required capability to expect in an advanced topic. The students shall develop capabilities allowing them to understand and intervene in the selection and/or development of new materials for application in the field of medical devices. On the other side, students are exposed to advanced technologies to design, plan, and development of materials, including nanotechnologies. This knowledge will allow students to understand, and conceive the relationships between material surfaces and the cellular environment and extracellular matrices.
By the end of the Subject, the students are prepared to: i) critically analyze scientific documentation and undertake research and development work in Biomaterials, ii) know the legislation, regulations and standards in force associated with the development of a new biomaterial and its placement in the Marketplace.
Working method
Presencial
Program
Analysis of case studies dedicated particularly to advanced applications of biomaterials:
- Applications of microfluidics for liquid biopsy in cancer diagnosis and follow-up;
-Organ-on-a-chip for in vitro simulation of organ tissues;
-Nanosystems for controlled and local drug release;
- Scaffolds for tissue and organoid regeneration.
Bioreactors.
Biological Glues.
Textile Structures - production methods and characterization of fibrous structures.
The new European Regulation for Medical Devices – MDR: Pre-clinical tests and their ethical/ legal interpretation. Ethical and regulatory aspects of medical devices. Standards applied to clinical trials.
3D Biomodeling. Techniques of medical image acquisition. Additive manufacturing for 3D structure processing. 3D printing.
Mandatory literature
Buddy D. Ratner;
Biomaterials science. ISBN: 0-12-582463-7
Fernando Jorge Alves;
Protoclick- Protototipagem Rápida
Teaching methods and learning activities
Lecturing this subject involves a diversified character, involving components of thematic presentations, eventually with contributions from some external experts, but also with most appreciated participation of students in developing presentation materials, mostly based in their very heterogeneous backgrounds, making them agents of their own training process
Evaluation Type
Distributed evaluation with final exam
Assessment Components
| Designation |
Weight (%) |
| Apresentação/discussão de um trabalho científico |
30,00 |
| Teste |
70,00 |
| Total: |
100,00 |
Amount of time allocated to each course unit
| Designation |
Time (hours) |
| Apresentação/discussão de um trabalho científico |
43,00 |
| Estudo autónomo |
80,00 |
| Frequência das aulas |
39,00 |
| Total: |
162,00 |
Eligibility for exams
Students must obtain a minimum score of 10 in the theoretical exam of the UC and in the bibliographic research work.
Calculation formula of final grade
Final classification: 70% for the theoretical exam and 30% for the bibliographic research work.
Special assessment (TE, DA, ...)
The classification will be obtained through a theoretical exam, and the student has to carry out the work of biographical research.
Classification improvement
The improvement of classification will be obtained through a theoretical exam, taking into account the component already obtained in the bibliographic research work.